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The potential of betulin and betulinic acid derivatives

Over the last few years, researchers have conducted numerous studies to investigate the therapeutic value of betulin. But “numerous” still doesn’t suffice. It has already been shown that betulin-based products hold promise for new treatment modalities, although they do require further research. The chances are, they have unknown beneficial effects that may complement the existing ones:

To find the needed derivative among our range of products, you can type its name or CAS number in the search bar. Keep in mind that most of the substances are available in small quantities. If you want to make a large order for your R&D or request more details, please Contact us.

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Nature Science Technologies

Nature Science Technologies specializes in small scale supply, development and custom syntheses of a wide variety of betulin derivatives for drug discovery (medicinal chemistry, screening) as well as the analytical standards. These include amine, alkyne and azide derivatives of betulin, betulinic acid, betulonic acid. The source of these semi-synthetic products is betulin, produced by the nature.

Our current product portfolio contains over 40 betulin derivatives. Nature Science Technologies produces these products for R&D purposes on a gram scale and with a high quality.

Betulin derivatives and other products for R&D under one roof

   It’s common knowledge that bringing a new drug to the market takes years of research, hundreds of clinical trials, and billions in investments. At Nature Science Technologies, we proudly assist R&D companies in expediting this process by providing them with betulin-derived substances for sale. Our aim is to contribute to the screening effectiveness and open up more click chemistry opportunities for the development of new compounds. With this in mind, we are ready to fulfill small-scale orders for betulin and betulinic acid derivatives to trigger substantial advances.

   Betulin is naturally found in abundance and traditionally extracted from the birch bark. It then serves as a precursor for a range of azido, amino, alkynyl and other triterpenoid derivative products for drug discovery, which are all available in our online catalog. Currently, it’s made up of more than 40 substances measured in gram scale. All you have to do is to decide on the weight option of the coveted semi-synthetic derivative of betulin and buy it on our website.

   At Nature Science Technologies, we ensure excellent quality of all the available products. While reinforcing the importance of meeting substance specifications, we provide a certificate of analysis for every single order, be it betulin acid or an azido-type derivative. In the product description part, you can find the details regarding purity, appearance, etc.

Birch Bark Extraction

Extract ingredients

Betulin

Betulinic acid

Lupeol

Betulin Caffeate

Natural antioxidants

FAQ

Most frequent questions and answers

Betulin is a natural bioactive compound (a pentacyclic triterpenoid) derived from birch bark and its extract. The positive effects of betulin are well known in folk medicine, where birch bark is a common remedy for the treatment of several skin diseases, making it a popular additive in many cosmetics.

New and improved methods of extracting Betulin have lead to higher yields of the active ingredients found in this versatile compound, and medical studies have shown betulin to be effective against high cholesterol, high blood pressure and obesity, with the compound also being shown to possess promising antiviral, antibacterial and anticancer properties.

Betulinic acid (Betulin acid) is a naturally occurring bioactive compound found in many plants. Due to its increased bioavailability, it shows higher potency in medicine and cosmetics than betulin itself. Betulinic acid serves as a popular additive in cosmetics and food supplementation, with research also showing positive applications for the reduction of cholesterol and the treatment of several types of cancer, whilst also exhibiting antibacterial, antiviral and anti-inflammatory properties.

Betulin can be isolated from the bark of the white birch, where it comprises up to 30% of the tree’s dry mass. Green organic solvent is used to make birch bark extract, where the content of betulin is about 70-80%. After this process has been completed, the purity of betulin is increased to 98% and even higher depending on the needs of the buyer.

Betulin and betulinic acid are most commonly used as additives in cosmetics, where they serve as natural skin toners, skin restorers and antioxidants. They can also aid in the treatment of dermatitis, psoriasis and eczema. Both betulin and betulinic acid are also used in betulin supplements, and have been shown to improve several metabolic processes and also help with the treatment of high cholesterol and diabetes. Betulin has also found a place in clinics as a possible anticancer agent.

Betulin benefits include the restoration and improvement of skin, mostly due to a reduction in oxidative stress. Research also suggests that betulin and betulinic acid can help to regulate blood sugar levels by increasing insulin sensitivity, in turn helping to prevent diet-induced obesity. Others report that betulin and betulinic acid can aid in lowering cholesterol, and in some cases, can also help to maintain normal blood pressure.

Clickbetulin.com can provide you with betulin and betulinic acid in food and cosmetic grades of purity depending upon your needs, as well as several semi-synthetic derivatives for R&D purposes. If you can’t find exactly what you’re looking for, please contact our sales team at: sales@clickbetulin.com

You can order high quality betulin and betulinic acid directly from our online store, and if you have any questions about our products or their possible applications, please head over to our contact page and get in touch!